Amino-Fucoidan as Vector of rtPA to the Clot Ghebouli et al

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Supplementary Fig. S2 Rotem analysis. (A) Representative human whole blood thromboelastogram (ROTEM) profiles. Venous blood was preincubated with a sub-threshold recombinant tissue plasminogen activator (rtPA) alone (1.1 nmol/L), rtPA/DLF (1.1 nmol/L), NF alone, DLF alone and rpTF/NF. (B) In each condition, the rate of fibrinolysis was assessed by the reduction of the amplitude of the thromboelastogram profile at 60 minutes. Data are mean % SEM; p < 0.05; significantly different (n 1⁄4 3, 4). DLF, dilysine fucoidan; NF, native fucoidan; SEM, standard error of mean.

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تاریخ انتشار 2017